Publications | Madapura Lab

Olley G, Pradeepa M M, FitzPatrick D R., Bickmore W A. , Boumendil C., Cornelia-de Lange syndrome-associated mutations cause a DNA damage signalling and repair defect BioRxiv 2019 https://www.biorxiv.org/content/10.1101/632992v1.full (2019). Cornelia-de Lange syndrome-associated mutations cause a DNA damage signalling and repair defect. bioRxiv.

De Vas M G, Garstang M G, Joshi S S, Khan T, Atla G, Parry D , Moore D, Cebola I, Zhang S, Cu W, Lampe A K, Lam W W , FitzPatrick D R , Pradeepa M M* and Atanur S S* De novo mutations in fetal brain-specific enhancers play a significant role in severe intellectual disability. BioRxiv 2019 https://www.biorxiv.org/content/10.1101/621029v1 *corresponding author (2019). De novo mutations in fetal brain specific enhancers play a significant role in severe intellectual disability. bioRxiv.

Olley G, Ansari M, Bengani H, Grimes GR, Rhodes J, Kriegsheim AV, Blatnik A, Stewart F J, Ross A, Bickmore WA, Pradeepa MM * , and FitzPatrick DR * . BRD4 interacts with NIPBL and is mutated in a Cornelia de Lange-like syndrome. Nature Genet. 2017 in press https://www.nature.com/articles/s41588-018-0042-y * Corresponding author (2018). BRD4 interacts with NIPBL and is mutated in a Cornelia de Lange-like Syndrome.. Nature Genetics, 50(3).

Pradeepa M M, McKenna F, Taylor GCA, Bengani H, Grimes GR, Wood A, Bhatia S, and Bickmore W A. (2017) Psip1/p52 regulates distal Hoxa genes through activation of lncRNA Hottip PloS Genet 13, e1006677 (2017). https://doi.org/10.1371/journal.pgen.1006677 A perspective article highlighting this work is published in PloS Genet (2017). Psip1/p52 regulates posterior Hoxa genes through activation of lncRNA Hottip. PLoS Genetics, 13(4).

Pradeepa M M, Grimes G R, Kumar Y, Olley G, Taylor G, Schneider R and Bickmore W A. Histone H3 globular domain acetylations identifies new class of enhancers Nature Genet. 2016 https://doi.org/10.1038/ng.3550 * Corresponding author (2016). Histone H3 globular domain acetylation identifies a new class of enhancers.. Nature Genetics, 48(6).

Taylor G, Eskeland R, Balkan B H, Pradeepa M M & Bickmore W A* (2013) H4K16 acetylation marks active genes and enhancers of embryonic stem cells but does not alter chromatin compaction. https://genome.cshlp.org/content/23/12/2053.full Genome Res, Corresponding author (2013). H4K16 acetylation marks active genes and enhancers of embryonic stem cells, but does not alter chromatin compaction.. Genome Res, 23(12).

Pradeepa, M M., Sutherland, H. G., Ule, J., Grimes, G. R., & Bickmore, W. A. (2012). Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing. https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1002717 PLoS Genet, 8(5), e1002717. doi:10. (2012). Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing.. PLoS Genet, 8(5).